Cystatin C Reagent

Key Benefits of the Randox Cystatin C Reagent

Exceptional correlation with standard methods

The Randox methodology was compared against other commercially available methods and the Randox Cystatin C assay showed a correlation coefficient of r=1.00

Wide measuring range

The healthy range for Cystatin C is 0.57 – 1.05 mg/l. The Randox assay can comfortably detect levels outside of the healthy range measuring between 0.4 – 10 mg/l

Excellent stability

Stable on board the analyser for 28 days when stored at +10⁰C

Other features of the Randox Cystatin C Reagent

  • Latex Enhanced Immunoturbidimetric method
  • Liquid ready-to-use reagents
  • Stable until expiry date when stored at +2 to +8⁰C
  • Measuring range 0.4 – 10 mg/l
  • Intra-assay precision 4.2% at 0.78 mg/l and 2.6% at 5.35 mg/l
  • Total precision 6.2% at 0.78 mg/dl and 4.4% at 5.35 mg/dl
  • No need to measure urine to get a true Glomerular Filtration Rate
Cat NoSizeAnalyserEasy Read
Easy Fit
CYS4004R1 2 x 17.6ml
R2 2 x 6.1ml
RX Daytona/Imola
Hitachi 717/911/912/704/902

Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers.  Contact us to enquire about your specific analyser.

What is the Cystatin C assay used for?

What is Cystatin C?

Cystatin C is a small protein produced by bodily cells. It travels in the bloodstream to the kidneys where is is freely filtered by the glomerular membrane and then broken down at a constant rate.

What is the Cystatin C assay used for?

The Randox Cystatin C assay is used for the quantitative in vitro determination of cystatin C in serum and plasma to assess renal function. The best indicator of kidney function and to determine the level of renal impairment is the glomerular function rate (GFR). GFR is calculated based on age, gender, religion which is then compared against the level of cystatin C in the blood. For more information on chronic kidney disease, please click here [external link].

Cystatin C is not the traditional test to estimate GFR, however, there are several studies that have documented the superiority of of this assay compared to creatinine as a marker of GFR function.  Unlike creatinine, cystatin C does not have a ‘blind area’ meaning it is extremely sensitive to very small changes in GFR and therefore capable of detecting early reductions in GFR. GFR estimates based on this superior assay are less influenced by diet or muscle mass compared to GFR estimates based on creatinine, therefore, this superior assay is also beneficial if the patient is overweight, elderly or has a lot of muscle mass. It is also beneficial if previous kidney function tests were inconclusive.

  • Zati Iwani, A.K., et al. The usefulness of cystatin C as a marker for chronic kidney disease. Universal Journal of Clinical Medicine. 2013, 1(2): 28-33)

Specific Proteins Panel

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Diabetes Panel

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