Copper Reagent

Key Benefits of the Randox Copper reagent

Exceptional correlation with standard methods

The Randox methodology was compared against other commercially available methods and the Randox Copper assay showed a correlation coefficient of r=0.99

Wide measuring range

The Randox Copper reagent can comfortably detect levels outside of the healthy range measuring between 6.6 – 86 µmol/l

Excellent stability

Stable for 2 weeks when stored at +2 to +8°C

Other features of the Randox Copper reagent

  • Colorimetric method
  • Lyophilised reagents
  • Stable for 2 weeks when stored at +2 to +8°C
  • Measuring range 6.6 – 86 μmol/l
Cat NoSizeAnalyserEasy Read
Easy Fit
(S) Indicates standard included in kit
CU2340R1 5 x 20ml (S)
R2 1 x 30ml
RX Daytona/Imola--

Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers.  Contact us to enquire about your specific analyser.

What is Copper assay used for?

What is Copper?

Copper is an essential trace mineral in human nutrition and a component of many metalloenzymes. It is mainly found in the brain, liver, kidneys, heart and skeletal muscle with the highest quantities found in the liver and muscles. It aids in some of the key bodily functions including: the production of red blood cells, the maintenance of nerve cells and the immune system, the formation of collagen to absorb iron for energy production, and the formation of melanin, bone and connective tissue. Ceruloplasmin is the protein responsible for the transportation of it around the body.

What is the Copper assay used for?

The Randox Copper assay is used to measure the amount of copper in the blood; to help with diagnosis and monitoring of conditions related to deficiency or toxicity including Wilson disease. There are various health problems that can cause abnormal copper levels, however deficiency is less likely than toxicity because a normal diet contains plenty of copper including organ meats, beans and wholegrains. Deficiency is more likely to occur in those who are malnourished, more likely children.

Deficiency is more commonly occurs in premature babies, resulting in bone abnormalities and fractures. Menkes disease is a rare inherited genetic disorder of copper metabolism and is characterised by sparse, kinky hair as children with this disorder are unable to absorb enough copper. For more information on Menkes disease, please click here [external link].

Toxicity can be caused by consuming too many dietary supplements high in copper, from drinking contaminated water, or from fungicides containing copper sulphates. Wilson disease prohibits the liver from safely storing and excreting it resulting in it seeping out of the liver and building up in the eyes, kidneys and brain causing nerve damage, and if untreated, it can be fatal. For more information on Wilson disease, please click here [external link].

  • Squitti, R., et al. D-penicillamine reduces serum oxidative stress in Alzheimer‘s disease patients. Eur. J. Clin. Invest. 2002, 32(1): 51-59
  • Squitti, R., et al. Excess of serum copper not related to ceruloplasmin in Alzheimer disease. Neurology 2005, 64(6): 1040-1046
  • Değer, Y., et al. Lipid peroxidation and antioxidant potential of sheep liver infected naturally with distomatosis. Türkiye Parazitologi Dergisi. 2008, 32(1): 23-26
  • Altamura, C., et al. Ceruloplasmin/transferrin system is related to clinical status in acute stroke. Stroke. 2009, 40(4): 1282-1288
  • Dobrzański, Z. et al. Effect of various feed phosphates on biochemical indices of blood and mineral composition of bones in finishing pigs. ACTA VET. BRNO. 2010, 79: 355-361

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